Derivatives of Aminobutanoic Acid Inhibiting Cpt

Derivatives of Aminobutanoic Acid Inhibiting Cpt

United States Patent Application 20080161395
Kind Code A1
Giannessi; Fabio ; et al. July 3, 2008

Abstract
The invention relates to a new class of compounds with action inhibiting carnitine palmitoyl transferase (CPT), pharmaceutical compounds which contain at least one new compound according to the invention, and their therapeutic use in the treatment of hyperglycaemic conditions such as diabetes and the pathologies associated with it, congestive heart failure and obesity.

Inventors: Giannessi; Fabio; (Pomezia, IT) ; Tassoni; Emanuela; (Ciampino, IT) ; Tinti; Maria Ornella; (Rome, IT) ; Conti; Roberto; (Rome, IT) ; Dell'Uomo; Natalina; (Pomezia, IT) ; Brunetti; Tiziana; (Pomezia, IT)
Correspondence Name and Address: LUCAS & MERCANTI, LLP
475 PARK AVENUE SOUTH, 15TH FLOOR
NEW YORK
NY
10016
US

Assignee Name and Adress: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
Rome
IT

Serial No.: 815068
Series Code: 11
Filed: February 13, 2006
PCT Filed: February 13, 2006
PCT NO: PCT/EP06/01290
371 Date: September 24, 2007

U.S. Current Class: 514/513; 560/169
U.S. Class at Publication: 514/513; 560/169
Intern'l Class: A61K 31/21 20060101 A61K031/21; C07C 229/02 20060101 C07C229/02; A61P 3/10 20060101 A61P003/10