Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy

Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy

United States Patent Application 20080161604
Kind Code A1
Calvani; Menotti ; et al. July 3, 2008

Abstract
The use of acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is described for the preparation of a medicament useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which said symptoms are selected from the group consisting of pain, paraesthesia and hyperaesthesia, in which the acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.

Inventors: Calvani; Menotti; (Rome, IT) ; Amato; Antonino; (North Bethesda, MD)
Correspondence Name and Address: LUCAS & MERCANTI, LLP
475 PARK AVENUE SOUTH, 15TH FLOOR
NEW YORK
NY
10016
US

Assignee Name and Adress: Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Rome
IT

Serial No.: 912520
Series Code: 11
Filed: April 18, 2006
PCT Filed: April 18, 2006
PCT NO: PCT/EP06/61632
371 Date: February 15, 2008