Avandaryl Oral Warnings & Precautions
Avandaryl Oral Warnings & Precautions
WebMD
This medication may infrequently cause or worsen certain heart problems (congestive heart failure, heart attack). Seek immediate medical attention if you notice any symptoms of heart problems, including: swelling of the hands/feet, unusual/sudden weight gain, trouble breathing, chest pain/discomfort.
Who should not take this medication?
Check with your physician if you have any of the following:
Conditions:
Increased Cardiovascular Event Risk, Macular Edema, Heart Attack, Angina, Disease of the Arteries of the Heart, Disease of Inadequate Blood Flow to the Heart Muscle, Chronic Heart Failure, Severe Heart Failure, Chronic Heart Failure Not Suddenly Currently Controlled by Medication, Fluid in the Lungs, Hepatitis caused by Drugs, Liver Problems, Kidney Disease, Osteoporosis, Decreased Calcification or Density of Bone, Recent Operation, Body Temperature More Than 101 Degrees F, Visible Water Retention, Weight Gain, Weakened Patient, Broken Bone, Injury, A Mother who is Producing Milk and Breastfeeding, Severe Infection, Type 1 Diabetes Mellitus, Retinal Changes of Eye in a Patient with Diabetes, Low Blood Sugar, Pituitary Hormone Deficiency, Addison's Disease, Water Retention, Hepatic Porphyria, Habit of Drinking Too Much Alcohol
Avandaryl Oral Precautions
Before taking this medication, tell your doctor or pharmacist if you are allergic to rosiglitazone or glimepiride; or to other "glitazones" (e.g., pioglitazone); or if you have any other allergies.
Promptly talk with your doctor or pharmacist about the benefits and possible risks of this medication, even if you have been taking it for awhile, especially if you have heart problems. Do not stop taking it unless directed to do so.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: type 1 diabetes (insulin-dependent diabetes), very high blood sugar levels (diabetic ketoacidosis), newly diagnosed or worsening heart failure (acute congestive heart failure), history of liver disease, active liver disease.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., chronic congestive heart failure, heart attack, angina), fluid in your lungs, swelling (edema, fluid retention), kidney disease, thyroid problems, certain hormonal conditions (adrenal/pituitary insufficiency, SIADH-syndrome of inappropriate secretion of antidiuretic hormone), mineral imbalance (hyponatremia), anemia, high blood cholesterol, eye (retina) problems, bone problems (e.g., osteoporosis, osteopenia).
You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels; use caution engaging in activities requiring alertness such as driving or using machinery.
Limit alcohol while taking this medication because it can increase your risk of developing low blood sugar (hypoglycemia).
During times of stress, such as fever, infection, injury or surgery, it may be more difficult to control your blood sugar. Consult your doctor because a change in your medication may be required.
This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.
This medication may increase the risk of bone fracture (upper arm, hand, foot) in female patients. To lower the chance of getting injured, use caution when doing activities such as contact sports.
Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, the elderly may be at greater risk for hypoglycemia while using this drug.
This medication can cause changes in the menstrual cycle (promote ovulation) in women with certain fertility problems. Consult your doctor or pharmacist about the use of reliable birth control while taking this medication.
This medication is not recommended for use during pregnancy. Insulin treatment may be preferred. Use of rosiglitazone/glimepiride close to the expected delivery date may increase the risk of low blood sugar in your newborn. Consult your doctor for more details and follow all instructions carefully.
It is not known whether this medication passes into breast milk. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
What should I know before taking this medication?
If you are:
Pregnant:
Only When Necessary: RISK OF HYPOGLYCEMIA IN NEONATE IF USED NEAR DELIVERY
Nursing:
Absolute Contraindication: NOT RECOMMEND;EXCRETED IN RATS;POSSIBILITY OF HYPOGLYCEMIA IN NURSING INFANTS
An adult over 60:
Precaution: AGE & DECREASED RENAL FXN INCREASES RISK OF HYPOGLYCEMIA.
Giving this medication to a child under 12:
Warning: SAFETY & EFFICACY NOT ESTABLISHED IN CHILDREN LESS THAN 18 YRS
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