Peptides, derivatives and analogs thereof, and methods of using same

Peptides, derivatives and analogs thereof, and methods of using same

United States Patent 7,393,919
Levetan , et al. July 1, 2008

Abstract
Human proIslet Peptides (HIP) and HIP analogs and derivatives thereof, derived from or homologous in sequence to the human REG3A protein, chromosome 2p12, are able to induce islet neogenesis from endogenous pancreatic progenitor cells. Human proIslet Peptides are used either alone or in combination with other pharmaceuticals in the treatment of type 1 and type 2 diabetes and other pathologies related to aberrant glucose, carbohydrate, and/or lipid metabolism, insulin resistance, overweight, obesity, polycystic ovarian syndrome, eating disorders and the metabolic syndrome.

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Inventors: Levetan; Claresa S. (Bryn Mawr, PA), Upham; Loraine V. (Mt. Laurel, NJ)
Assignee: Cure DM, Inc. (Wynnewood, PA)

Appl. No.: 11/441,491
Filed: May 25, 2006

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Related U.S. Patent Documents

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Application Number Filing Date Patent Number Issue Date
60684819 May., 2005

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Current U.S. Class: 530/327
Current International Class: A61K 38/04 (20060101); A61K 38/00 (20060101)
Field of Search: 514/2 530/527