Humulin N: Drug Interactions: Humulin N is used by diabetics to lower their blood sugar. Like other insulin, many prescription or non-prescription medicines, vitamins, and herbal supplements can interact with Humulin N insulin and alter how effective it will be so let your prescribing physician know if you are taking any. Patients need know how to recognize low blood sugar symptoms; it can become dangerous if it goes too low. Monitor your blood sugar levels with a glucose monitor while you are using insulin or other diabetic medications; many health insurance plans will cover the cost of a glucose monitor.