Glucose mediates cognitive dysfunction in type 2 diabet...

Glucose mediates cognitive dysfunction in type 2 diabetes

Glucose mediates cognitive dysfunction in type 2 diabetes
2006
Katherine Sole
Nature Clinical Practice Neurology

Older adults with type 2 diabetes are known to be at an increased risk for cognitive dysfunction. It is unknown if this is related to chronically elevated glucose levels or insulin levels; however, the available evidence suggests that elevated insulin levels might be to blame. A US team has compared the effects of rosiglitazone (which increases insulin sensitivity) and glibenclamide (which encourages insulin production, and is also known as glyburide) on cognition in older patients with type 2 diabetes.

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