Janumet Official FDA Information, Side Effects, and use...

Janumet Official FDA Information, Side Effects, and uses.

Janumet Official FDA Information, Side Effects, and uses.
Drugs.com

Janumet

Generic Name: sitagliptin and metformin hydrochloride
Dosage Form: tablets

WARNING: LACTIC ACIDOSIS

Lactic acidosis is a rare, but serious complication that can occur due to metformin accumulation. The risk increases with conditions such as sepsis, dehydration, excess alcohol intake, hepatic insufficiency, renal impairment, and acute congestive heart failure.

The onset is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, increasing somnolence, and nonspecific abdominal distress.

Laboratory abnormalities include low pH, increased anion gap and elevated blood lactate.