What other drugs will affect metformin and rosiglitazone?
What other drugs will affect metformin and rosiglitazone?
Yahoo Health

You may be more likely to have hyperglycemia (high blood sugar) if you are taking metformin and rosiglitazone with other drugs that raise blood sugar. Drugs that can raise blood sugar include:

* isoniazid;
* diuretics (water pills);
* steroids (prednisone and others);
* phenothiazines (Compazine and others);
* thyroid medicine (Synthroid and others);
* birth control pills and other hormones;
* seizure medicines (Dilantin and others); and
* diet pills or medicines to treat asthma, colds or allergies.

You may be more likely to have hypoglycemia (low blood sugar) if you are taking metformin and rosiglitazone with other drugs that lower blood sugar. Drugs that can lower blood sugar include:

* some nonsteroidal anti-inflammatory drugs (NSAIDs);
* aspirin or other salicylates (including Pepto-Bismol);
* sulfa drugs (Bactrim and others);
* a monoamine oxidase inhibitor (MAOI);
* beta-blockers (Tenormin and others); or
* probenecid (Benemid).

Some medications may interact with metformin and rosiglitazone. Tell your doctor if you are using any of the following drugs:

* gemfibrozil (Gemcor);
* rifampin (Rifater, Rifadin, Rimactane);
* nifedipine (Adalat, Procardia);
* cimetidine (Tagamet) or ranitidine (Zantac);
* amiloride (Midamor) or triamterene (Dyrenium);
* digoxin (Lanoxin);
* morphine (MS Contin, Kadian, Oramorph);
* procainamide (Procan, Pronestyl, Procanbid);
* quinidine (Cardioquin, Quinidex, Quinaglute);
* trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra); or
* vancomycin (Vancocin, Lyphocin).

This list is not complete and there may be other drugs that can interact with metformin and rosiglitazone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Copyright 1996-2003 Cerner Multum, Inc. Version: 4.08. Revision date: 12/02/2007.